Rushen will open their defence of the Canada Life Premier League away to one of their biggest rivals.
The Spaniards will open their campaign away to St. Mary's.
Railway and Hospital Cup winners Peel will hope to end their opening day home jinx when they entertain Gymns at Douglas Road.
F.A. Cup holders St. George's meet Douglas rivals Old Boys at Glencrutchery Road.
Douglas Royal and Corinthians begin life at Ballafletcher with a "derby" against each other.
Laxey are at home to Ramsey and newly promoted Ayre welcome Castletown to Andreas.
The opening league matches will be played on Saturday 14th August.
Rushen meet St. George's in the Eric Fletcher Charity Shield match on Sunday 8th August.

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