It's been described as the 'disease of the 21st century'.
One in 50 people will get it and a quarter of them will die.
Those are the sobering facts on melanoma, for which there is no guaranteed cure.
It's Melanoma Awareness Week, and Isle of Man residents are being urged to wise-up to the symptoms and the vital need for early diagnosis.
Harry Townsend set up Britain's first Melanoma charity in the name of his late wife Myfanwy who died of the disease.
He says the key is to check our moles regularly (audio file attached):
Researching your Manx family history can be a very interesting and rewarding hobby. Trace your roots in the Isle of Man with our helpful of guide.
