Canada Life Premier League Champions St. George's will be presented with the trophy after Wednesday evening's match away to Peel at Douglas Road.
Geordies have already wrapped up the title - their 9th success in the last 11 years - and are on course for a second Grand Slam in the last three seasons.
They have also secured the Railway and F.A. Cups and play at Peel again on Sunday in the Hospital Cup Quarter-Finals.
Elsewhere, St. Mary's will be confirmed as runners-up if they draw or win at home to Michael - victory for the away side would condemn Castletown to relegation.
Ramsey welcome Old Boys to Ballacloan Stadium and Union Mills entertain Ramsey Youth Centre.
In JCK Division Two, Ayre and Marown clash with both sides chasing promotion to the Premier League.
Other contenders Douglas Royal go to Pulrose and leaders Gymns travel to Billygoat Park for a game with bottom team Foxdale.
Malew play Onchan in the other Division Two fixture.
Researching your Manx family history can be a very interesting and rewarding hobby. Trace your roots in the Isle of Man with our helpful of guide.
